UAN: 388-000-10-201-L01-P

Faculty:
HARTMUT DERENDORF, PhD; Univ. of Florida, Gainesville, FL.
JOHAN W. MOUTON, MD, PhD; Canisius Wilhelmina Hosp., Nijmegen, Netherlands.
WILLIAM A. CRAIG, MD; Univ. of Wisconsin, Madison, WI.
ALASDAIR MACGOWAN, MD; Bristol Ctr. for Antimicrobial Res., Bristol, United Kingdom.
URSULA THERURETZBACHER, PhD; Ctr. for Anti-Infective Agents, Vienna, Austria.

Pharmacokinetics and Pharmacodynamics (PK/PD) have now become essential tools for determining the appropriate use of currently available anti-infective agents as well as for accelerating the development of new drugs. While this is now more and more recognized by Academia, Industry and Regulatory Agencies there is presently a lack of training into these disciplines. The aim is to train people professionally involved in development or in the use of anti-infective drugs in the basic and applied aspects of pharmacokinetics and pharmacodynamics, showing how these sciences have emerged over the last 20 years and how their influence has grown.

Objectives:
Upon completion of this workshop, the participant should be able to:

• Discuss pharmacokinetic and pharmacodynamic concepts of antimicrobial efficacy;
• Apply in vitro models and animal models in pharmacodynamic research;
• Recognize the limitations and use of serum and tissue concentrations;
• Calculate pharmacokinetic and pharmacodynamic parameters and interpret the results; and
• Assess drug resistance in vitro.

Intended Audience: Medical microbiologists, infectious diseases specialists, pharmacologists, drug development scientists, and other interested participants.
Course Level: Beginning
Prerequisites: None